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Nitric Oxide Synthase (eNOS/iNOS) Pathway Regulation Stimulates NO production through eNOS/iNOS activation : BPC-157 upregulates nitric oxide synthesis in vascular tissue and restores endothelial homeostasis, as shown in ischemic and inflammatory models 3,4

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Briefly, COS cells were transfected with an expression plasmid encoding 3MST- or rhodanese-cDNA using TransIT-LT1 Transfection Reagent (Mirus Bio, Madison, WI, USA) following the procedure recommended by the manufacturer

Traumatic brain injury (TBI): Studies indicate that BPC-157 reduces oxidative stress, neuronal apoptosis, and neuroinflammation , leading to improved cognitive recovery in animal models (Gavrilovic et al., 2016)